UpToDate This link opens in a new windowUpToDate is the most widely used clinical decision support solution in the world. UpToDate’s evidence based content is comprised of more than 10,500 clinical topics across 24 specialties. A team of physician authors and editors continuously review more than 470 medical journals to ensure that the content is current and fully referenced. Also included in UpToDate is access to 5,400 unique drug entries, a drug interaction tool, 28,000 graphics, and 160 commonly used medical calculators.